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    From Cardiovascular System

    Femoral Arteries
    Main arteries supplying the thighs.
    Internal Iliac Veins
    Drain pelvic organs.
    Dorsalis Pedis Arteries
    Supply blood to the dorsal surface of the foot.
    Superior Vena Cava
    Returns deoxygenated blood from upper body.
    Basilic Veins
    Superficial veins of the medial upper limb.
    Left Inferior Pulmonary Vein
    Returns oxygenated blood from left lung.
    Heart
    Muscular organ responsible for pumping blood throughout the body.
    Fossa Ovalis
    Remnant of the fetal foramen ovale.
    Abdominal Aorta
    Part of descending aorta within the abdomen.
    Small Saphenous Vein
    Superficial vein of the posterior leg.
    External Iliac Arteries
    Continue into the legs as femoral arteries.
    Thoracic Aorta
    Part of descending aorta within the chest.
    Aortic Arch
    Curved portion of the aorta giving rise to major arteries.
    Subclavian Veins
    Carry blood from the upper limbs to the heart.
    Pulmonary Trunk
    Carries deoxygenated blood from right ventricle to lungs.
    Tricuspid Valve
    Valve between the right atrium and right ventricle.
    Inferior Vena Cava
    Returns deoxygenated blood from lower body.
    External Jugular Veins
    Drain blood from the face and scalp.
    Median Cubital Vein
    Connects cephalic and basilic veins at the elbow.
    Internal Iliac Arteries
    Supply blood to pelvic organs.
    Common Iliac Veins
    Drain blood from the pelvis and lower limbs.
    Visceral Layer (Epicardium)
    Covers the external surface of the heart.
    Internal Carotid Artery
    Supplies blood to the brain.
    Left Subclavian Artery
    Supplies the left upper limb.
    Crista Terminalis
    Smooth muscular ridge in the right atrium.

    Papillary Muscles

    Reviewed by our medical team

    Muscles that anchor the heart valves via chordae tendineae.

    Overview

    Papillary muscles are cone-shaped muscular projections from the inner walls of the ventricles of the heart. They attach to the atrioventricular (AV) valve leaflets — the mitral and tricuspid valves — via the chordae tendineae. Their primary role is to prevent prolapse or inversion of these valves during ventricular systole. By contracting in synchrony with the ventricular myocardium, they help maintain unidirectional blood flow and contribute to the mechanical efficiency of the heart.

    Location

    Papillary muscles are found in both ventricles of the heart:

    • Right ventricle: Contains three papillary muscles associated with the tricuspid valve — anterior, posterior, and septal papillary muscles.

    • Left ventricle: Contains two papillary muscles attached to the mitral valve — anterolateral and posteromedial papillary muscles.

    They originate from the ventricular walls and extend into the chamber, projecting toward the AV valves. The chordae tendineae link these muscles to the valve leaflets, forming an integrated mechanism that supports valve closure during contraction.

    Structure

    Each papillary muscle is a muscular ridge composed of:

    • Myocardial tissue: Composed of contractile cardiac muscle fibers.

    • Attachment base: Anchored to the ventricular wall.

    • Apex: Gives rise to chordae tendineae, fibrous cords that attach to the free edges of valve leaflets.

    The papillary muscles are an integral part of the valve complex. They have a rich blood supply, predominantly from branches of the coronary arteries — particularly the left anterior descending and right coronary arteries.

    Function

    The main function of the papillary muscles is to:

    • Stabilize valve leaflets during ventricular contraction (systole)

    • Prevent valve prolapse into the atria by maintaining tension via the chordae tendineae

    • Support effective valve closure to maintain unidirectional blood flow through the heart

    Their contraction is timed precisely with the contraction of the ventricular myocardium, ensuring that the valve leaflets close securely without inverting into the atria under high pressure.

    Physiological Role(s)

    Papillary muscles serve critical physiological roles in maintaining heart function:

    • Valve integrity: By anchoring the chordae tendineae, they preserve the geometry and function of the AV valves.

    • Hemodynamic stability: Proper function ensures efficient forward flow of blood, minimizing regurgitation.

    • Conduction synchronization: Papillary muscle contraction is coordinated with the ventricular electrical cycle via the Purkinje fibers, especially in the case of the moderator band and anterior papillary muscle of the right ventricle.

    Any disruption in their contraction or anatomy can result in compromised valve function and reduced cardiac output.

    Clinical Significance

    Papillary muscles are involved in several important cardiac conditions:

    • Papillary Muscle Rupture: A rare but life-threatening complication of myocardial infarction, especially involving the posteromedial papillary muscle (which typically has a single blood supply). It leads to acute mitral regurgitation and pulmonary edema.

    • Ischemic Papillary Dysfunction: Chronic ischemia can weaken these muscles, impairing their ability to tense the valve leaflets, resulting in functional mitral or tricuspid regurgitation.

    • Mitral Valve Prolapse (MVP): Elongated or weakened chordae tendineae, sometimes linked to papillary muscle dysfunction, can lead to leaflet prolapse and valve incompetence.

    • Hypertrophic Cardiomyopathy (HCM): Abnormal positioning or hypertrophy of papillary muscles can obstruct the left ventricular outflow tract and contribute to mitral regurgitation.

    • Echocardiographic Assessment: Papillary muscle motion is routinely evaluated in echocardiography to assess valvular function and detect infarction-related damage.

    • Surgical and Transcatheter Interventions: In mitral valve repair or replacement, preservation or reconstruction of papillary muscle-chordal integrity is crucial to restoring normal valve function.

    Recognition of papillary muscle anatomy, perfusion, and function is essential in diagnosing and managing valvular heart disease, post-infarction complications, and congenital abnormalities.

    Did you know? The heart is located between your lungs, slightly to the left.